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## AMP Group Unveils New Draft Guidelines for Interpreting, Reporting Cancer Sequencing Variants

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The draft guidelines include language on reporting biomarkers predicting therapy response or resistance, liquid biopsy, and mutational signatures like TMB, MSI, and HRD.

## Biomodal Sues Watchmaker Genomics Over Methylation Sequencing IP

Both Watchmaker and Biomodal are commercializing sequencing-based methylation detection assays that use TET enzymes.

## Q&A: George Church on Widespread Genomic Sequencing, Xenotransplantation, and Shepherding Change

The geneticist and entrepreneur highlights his aspirations, moments of personal fulfilment, and the leading edge for science and society.

## Study Outlines Cybersecurity Risks of Portable Sequencers

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An analysis by University of Florida researchers exposed three security vulnerabilities in the Oxford Nanopore MinIon device that have since been fixed by the company.

## Multiomics Study of Pig Kidney Transplant in Brain-Dead Recipient Reveals Immune Responses

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After transplanting a gene-edited pig kidney into a brain-dead human recipient, researchers used multiomic and physiological tests to follow the effects over two months.

## Grail Reports 26 Percent Q3 Revenue Rise, Expects Galleri Test FDA Submission in Early 2026

Grail tallied $36.2 million in revenues compared to $28.7 million a year ago as revenue from sales of its Galleri cancer early detection test grew 29 percent year over year.

## Natera, Flatiron Health Partner on Integrating Cancer Tests Into OncoEMR Platform

The partnership aims to make it easier to incorporate minimal residual disease testing and monitoring into routine cancer care.

## Single-Cell Sequencing Reveals Distinct Form of Treatment-Resistant Pediatric Leukemia

Using single-cell RNA-seq, researchers narrowed in on non-canonical, treatment-resistant T-cell acute lymphoblastic leukemia blasts marked by enhanced ZBTB16 expression.

## Baylor Genetics to Provide PGx, Germline Genetic Testing to Veterans Affairs Department

Under the multiyear contract, both pharmacogenomics and germline cancer testing services are available to all veterans across the VA healthcare system.

Business, Policy & Funding

- ## Bio-Rad to Commercialize UMich Digital PCR Assay for HPV-Positive Head and Neck Cancer Recurrence

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- ## ABL Diagnostics Inks French Distribution Alliance With Eurobio Scientific
- ## Becton Dickinson Onclarity HPV Test Gets WHO Prequalification
- ## Top Five Articles on GenomeWeb Last Week: Sophia Genetics NGS Deals, Biomodal Sues Watchmaker, More
- ## People in the News at Oxford Nanopore, 10x Genomics, SMi Systems, Freenome, ACMG

Technology

- ## Bio-Rad to Commercialize UMich Digital PCR Assay for HPV-Positive Head and Neck Cancer Recurrence

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- ## Thermo Fisher Touts Turnaround Time of Comprehensive Genomic Profiling Assay at AMP

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- ## Roche Gives Glimpse of Cancer Genomics Potential of New Axelios Sequencer

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- ## Inflammatory Bowel Disease-Related Transcripts Shed From Gut Reveal Immune, Intestinal Functions
- ## AVE Alliance Aims to Improve Variant Effect Prediction via Data Sharing, Analytic Guidelines

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Research & Discovery

- ## AVE Alliance Aims to Improve Variant Effect Prediction via Data Sharing, Analytic Guidelines

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- ## HUPO Annual Meeting Highlights Emerging Applications, Technologies in Proteomics Research

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- ## Biomodal Sues Watchmaker Genomics Over Methylation Sequencing IP
- ## Q&A: George Church on Widespread Genomic Sequencing, Xenotransplantation, and Shepherding Change
- ## Multiomics Study of Pig Kidney Transplant in Brain-Dead Recipient Reveals Immune Responses

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Diagnostics

- ## Bio-Rad to Commercialize UMich Digital PCR Assay for HPV-Positive Head and Neck Cancer Recurrence

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- ## Roche Gives Glimpse of Cancer Genomics Potential of New Axelios Sequencer

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- ## Becton Dickinson Onclarity HPV Test Gets WHO Prequalification
- ## Labcorp, Lunit Collaborating to Combine AI, Digital Pathology for Cancer Research
- ## After LDT Win, AMP Prepared to Take on Additional Regulatory, Legislative Challenges

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Applied Markets: Ag-Bio, Veterinary, Forensics, Food Safety, & Environmental Testing

- ## Primerdesign Inks UK Distribution Pact With Scientific Laboratory Supplies
- ## Qlucore Inks China Distribution Pact for Data Analysis Software Suites

Disease Areas

- ## Bio-Rad to Commercialize UMich Digital PCR Assay for HPV-Positive Head and Neck Cancer Recurrence

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- ## Inflammatory Bowel Disease-Related Transcripts Shed From Gut Reveal Immune, Intestinal Functions
- ## Becton Dickinson Onclarity HPV Test Gets WHO Prequalification
- ## Rare Variant Study Uncovers Brain Biology-Related ADHD Contributors
- ## ACMG Publishes Ovarian, Breast Cancer Risk Management Resource for RAD51C, RAD51D, BRIP1 Carriers

Breaking News

- ## Inflammatory Bowel Disease-Related Transcripts Shed From Gut Reveal Immune, Intestinal Functions
- ## ABL Diagnostics Inks French Distribution Alliance With Eurobio Scientific
- ## Becton Dickinson Onclarity HPV Test Gets WHO Prequalification
- ## Top Five Articles on GenomeWeb Last Week: Sophia Genetics NGS Deals, Biomodal Sues Watchmaker, More
- ## Labcorp, Lunit Collaborating to Combine AI, Digital Pathology for Cancer Research

Recent Headlines from 360Dx

- ## Despite Improvements, 'Significant Bottlenecks' Remain to Obtaining CE-IVD Marks in Europe

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- ## Siemens Healthineers Prepares for Possible Changes by Parent Firm as Q4 Dx Revenues Fall 4 Percent

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- ## With €46M in Funding, Deciphex Expands Digital Pathology Toolset and Reach

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- ## Sequencing, Proprietary Assays, and Infectious Disease MDx Drive Clinical Lab Growth Post-COVID

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- ## Queen Mary Spinout Procyon Targeting Early 2026 for Pancreatic Cancer Test Launch

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What's Popular?

- ## AI Protein Design Tools Pose Biosecurity Risks for DNA Makers

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- ## AMP Group Unveils New Draft Guidelines for Interpreting, Reporting Cancer Sequencing Variants

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- ## People in the News at Oxford Nanopore, 10x Genomics, SMi Systems, Freenome, ACMG
- ## Biomodal Sues Watchmaker Genomics Over Methylation Sequencing IP
- ## Volta Labs, New England Biolabs Partner to Develop Automated NGS Sample Prep Workflows

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